Names & Taxonomy

Uniprot ID:
B7Z2A4
Entry Name:
B7Z2A4_HUMAN
Status:
unreviewed
Protein Names:
Receptor-type tyrosine-protein phosphatase (EC 3.1.3.48)
Organism:
Homo sapiens (Human)

Structure

Length:
813
Sequence:
MDDAVQITKISMDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEPWEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK

Function

Catalytic Activity:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
Gene Ontology Go:
integral component of membrane
protein tyrosine phosphatase activity
Gene Ontology Molecular Function:
protein tyrosine phosphatase activity
Gene Ontology Cellular Component:
integral component of membrane
Keywords:
Hydrolase
Membrane
Protein phosphatase
Receptor
Signal
Transmembrane
Transmembrane helix