Names & Taxonomy
- Uniprot ID:
- Q1ZYQ1
- Entry Name:
- Q1ZYQ1_HUMAN
- Status:
- unreviewed
- Protein Names:
- Tubulin, alpha 2 (Tubulin, alpha 2, isoform CRA_b) (cDNA FLJ77591, highly similar to Homo sapiens tubulin, alpha 2 (TUBA2), transcript variant 1, mRNA)
- Gene Names:
- TUBA2 hCG_19100
- Gene Names Orf:
- hCG_19100
- Gene Names Primary:
- TUBA2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 450
- Sequence:
- MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY
Subcellular location
- Subcellular Location:
- Cytoplasm, cytoskeleton
Function
- Function:
- Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
- Gene Ontology Go:
- cytoplasm
microtubule
GTP binding
GTPase activity
structural constituent of cytoskeleton
microtubule-based process - Gene Ontology Biological Process:
- microtubule-based process
- Gene Ontology Molecular Function:
- GTPase activity
GTP binding
structural constituent of cytoskeleton - Gene Ontology Cellular Component:
- cytoplasm
microtubule - Keywords:
- Cytoplasm
Cytoskeleton
GTP-binding
Microtubule
Nucleotide-binding
Publication
- PubMed ID:
- 11181995