Names & Taxonomy
- Uniprot ID:
- Q16348
- Entry Name:
- S15A2_HUMAN
- Status:
- reviewed
- Protein Names:
- Solute carrier family 15 member 2 (Kidney H(+)/peptide cotransporter) (Oligopeptide transporter, kidney isoform) (Peptide transporter 2)
- Gene Names:
- SLC15A2 PEPT2
- Gene Names Primary:
- SLC15A2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 729
- Sequence:
- MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSYYGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFDFVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLNLADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHSVQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVGEDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIEDIPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVLVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMIKLETKKTKL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Multi-pass membrane protein.
Function
- Function:
- Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides.
- Cross Reference Drug Bank:
- DB00855 DB01060 DB00415 DB08795 DB00542 DB01053 DB00833 DB01140 DB00456 DB00535 DB01413 DB00671 DB00274 DB00493 DB01333 DB00438 DB01415 DB01212 DB01112 DB00567 DB00672 DB01340 DB01147 DB01000 DB00485 DB00492 DB01016 DB00691 DB00731 DB00713 DB00790 DB00881 DB00178 DB01348 DB01124 DB00519 DB00302 DB00577 DB01610
- Gene Ontology Go:
- extracellular exosome
integral component of plasma membrane
plasma membrane
oligopeptide transporter activity
peptide:proton symporter activity
drug transport
ion transport
protein transport
proton transport
transmembrane transport
transport - Gene Ontology Biological Process:
- drug transport
ion transport
protein transport
proton transport
transmembrane transport
transport - Gene Ontology Molecular Function:
- oligopeptide transporter activity
peptide:proton symporter activity - Gene Ontology Cellular Component:
- extracellular exosome
integral component of plasma membrane
plasma membrane - Keywords:
- Alternative splicing
Complete proteome
Glycoprotein
Membrane
Peptide transport
Phosphoprotein
Polymorphism
Protein transport
Reference proteome
Symport
Transmembrane
Transmembrane helix
Transport