Names & Taxonomy
- Uniprot ID:
- Q14651
- Entry Name:
- PLSI_HUMAN
- Status:
- reviewed
- Protein Names:
- Plastin-1 (Intestine-specific plastin) (I-plastin)
- Gene Names:
- PLS1
- Gene Names Primary:
- PLS1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 629
- Sequence:
- MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILSVADSNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSTISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWHTISNFSQDIKDSRAYFHLLNQIAPKGGEDGPAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNPKLNLAFVANLFNTYPCLHKPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIRVPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLKSANKKTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGLNRIK
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm.
Function
- Function:
- Actin-bundling protein in the absence of calcium.
- Gene Ontology Go:
- brush border
extracellular exosome
terminal web
actin filament binding
calcium ion binding
structural constituent of cytoskeleton
intestinal D-glucose absorption
positive regulation of establishment of protein localization to plasma membrane
positive regulation of multicellular organism growth
regulation of microvillus length
terminal web assembly - Gene Ontology Biological Process:
- intestinal D-glucose absorption
positive regulation of establishment of protein localization to plasma membrane
positive regulation of multicellular organism growth
regulation of microvillus length
terminal web assembly - Gene Ontology Molecular Function:
- actin filament binding
calcium ion binding
structural constituent of cytoskeleton - Gene Ontology Cellular Component:
- brush border
extracellular exosome
terminal web - Keywords:
- Acetylation
Actin-binding
Calcium
Complete proteome
Cytoplasm
Metal-binding
Phosphoprotein
Polymorphism
Reference proteome
Repeat