Names & Taxonomy

Uniprot ID:
Q13585
Entry Name:
MTR1L_HUMAN
Status:
reviewed
Protein Names:
Melatonin-related receptor (G protein-coupled receptor 50) (H9)
Gene Names:
GPR50
Gene Names Primary:
GPR50
Organism:
Homo sapiens (Human)

Structure

Length:
617
Sequence:
MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEETPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKPVSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGHHVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELSASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDYHDVVVIDVEDDPDEMAV
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Function

Function:
Does not bind melatonin.
Gene Ontology Go:
integral component of plasma membrane
G-protein coupled receptor activity
identical protein binding
melatonin receptor activity
cell surface receptor signaling pathway
cell-cell signaling
G-protein coupled receptor signaling pathway
Gene Ontology Biological Process:
cell-cell signaling
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
Gene Ontology Molecular Function:
G-protein coupled receptor activity
identical protein binding
melatonin receptor activity
Gene Ontology Cellular Component:
integral component of plasma membrane
Keywords:
Cell membrane
Complete proteome
Disulfide bond
G-protein coupled receptor
Membrane
Polymorphism
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix
Interacts With:
Itself; P04731; P02795; Q7Z3I7

Publication

PubMed ID:
8647286 15489334 16778767 16436372