Names & Taxonomy
- Uniprot ID:
- Q13183
- Entry Name:
- S13A2_HUMAN
- Status:
- reviewed
- Protein Names:
- Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter)
- Gene Names:
- SLC13A2 NADC1 SDCT1
- Gene Names Primary:
- SLC13A2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 592
- Sequence:
- MATCWQALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQASSNVEEGSNNPTFELQEPSPQKEVTKLDNGQALPVTSASSEGRAHLSQKHLHLTQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNVVNFASWFSFAFPTMVILLLLAWLWLQILFLGFNFRKNFGIGEKMQEQQQAAYCVIQTEHRLLGPMTFAEKAISILFVILVLLWFTREPGFFLGWGNLAFPNAKGESMVSDGTVAIFIGIIMFIIPSKFPGLTQDPENPGKLKAPLGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSWGIPLFSLHSFPSWAQSNTTAQCLPSLANTTTPSP
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Function:
- Cotransport of sodium ions and dicarboxylates such as succinate and citrate.
- Cross Reference Drug Bank:
- DB00139
- Gene Ontology Go:
- extracellular exosome
integral component of plasma membrane
membrane
plasma membrane
low-affinity sodium:dicarboxylate symporter activity
dicarboxylic acid transport
transmembrane transport
transport - Gene Ontology Biological Process:
- dicarboxylic acid transport
transmembrane transport
transport - Gene Ontology Molecular Function:
- low-affinity sodium:dicarboxylate symporter activity
- Gene Ontology Cellular Component:
- extracellular exosome
integral component of plasma membrane
membrane
plasma membrane - Keywords:
- Alternative splicing
Complete proteome
Ion transport
Membrane
Polymorphism
Reference proteome
Sodium
Sodium transport
Symport
Transmembrane
Transmembrane helix
Transport