Names & Taxonomy

Uniprot ID:
P63267
Entry Name:
ACTH_HUMAN
Status:
reviewed
Protein Names:
Actin, gamma-enteric smooth muscle (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin)
Gene Names:
ACTG2 ACTA3 ACTL3 ACTSG
Gene Names Primary:
ACTG2
Organism:
Homo sapiens (Human)

Structure

Length:
376
Sequence:
MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cytoplasm, cytoskeleton.

Function

Function:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Gene Ontology Go:
blood microparticle
cell body
cell periphery
cytoplasm
cytosol
extracellular exosome
extracellular space
filopodium
lamellipodium
myosin filament
ATP binding
mesenchyme migration
muscle contraction
positive regulation of gene expression
Gene Ontology Biological Process:
mesenchyme migration
muscle contraction
positive regulation of gene expression
Gene Ontology Molecular Function:
ATP binding
Gene Ontology Cellular Component:
blood microparticle
cell body
cell periphery
cytoplasm
cytosol
extracellular exosome
extracellular space
filopodium
lamellipodium
myosin filament
Keywords:
ATP-binding
Acetylation
Alternative splicing
Complete proteome
Cytoplasm
Cytoskeleton
Disease mutation
Isopeptide bond
Muscle protein
Nucleotide-binding
Oxidation
Reference proteome

Publication

PubMed ID:
2377475 1710027 14702039 15815621 15489334 19015515 22223895 26228148 22960657 24777424 24337657 24676022