Names & Taxonomy
- Uniprot ID:
- P61278
- Entry Name:
- SMS_HUMAN
- Status:
- reviewed
- Protein Names:
- Somatostatin (Growth hormone release-inhibiting factor) [Cleaved into: Somatostatin-28; Somatostatin-14]
- Gene Names:
- SST
- Gene Names Primary:
- SST
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 116
- Sequence:
- MLSCRLQCALAALSIVLALGCVTGAPSDPRLRQFLQKSLAAAAGKQELAKYFLAELLSEPNQTENDALEPEDLSQAAEQDEMRLELQRSANSNPAMAPRERKAGCKNFFWKTFTSC
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Somatostatin inhibits the release of somatotropin.
- Cross Reference Drug Bank:
- DB00847
- Gene Ontology Go:
- extracellular region
extracellular space
neuronal cell body
hormone activity
cell surface receptor signaling pathway
cell-cell signaling
digestion
G-protein coupled receptor signaling pathway
hormone-mediated apoptotic signaling pathway
hyperosmotic response
negative regulation of cell proliferation
regulation of cell migration
response to acidic pH
response to amino acid
response to drug
response to heat
response to nutrient
response to steroid hormone
synaptic transmission - Gene Ontology Biological Process:
- cell-cell signaling
cell surface receptor signaling pathway
digestion
G-protein coupled receptor signaling pathway
hormone-mediated apoptotic signaling pathway
hyperosmotic response
negative regulation of cell proliferation
regulation of cell migration
response to acidic pH
response to amino acid
response to drug
response to heat
response to nutrient
response to steroid hormone
synaptic transmission - Gene Ontology Molecular Function:
- hormone activity
- Gene Ontology Cellular Component:
- extracellular region
extracellular space
neuronal cell body - Keywords:
- 3D-structure
Cleavage on pair of basic residues
Complete proteome
Disulfide bond
Hormone
Pharmaceutical
Polymorphism
Reference proteome
Secreted
Signal