Names & Taxonomy
- Uniprot ID:
- P59796
- Entry Name:
- GPX6_HUMAN
- Status:
- reviewed
- Protein Names:
- Glutathione peroxidase 6 (GPx-6) (GSHPx-6) (EC 1.11.1.9)
- Gene Names:
- GPX6
- Gene Names Primary:
- GPX6
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 221
- Sequence:
- MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFAGKHVLFVNVAAYUGLAAQYPELNALQEELKNFGVIVLAFPCNQFGKQEPGTNSEILLGLKYVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIRWNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQFNTH
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted
Function
- Catalytic Activity:
- 2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
- Active Site:
- ACT_SITE 73 73
- Cross Reference Drug Bank:
- DB00143
- Gene Ontology Go:
- extracellular region
glutathione peroxidase activity
response to oxidative stress - Gene Ontology Biological Process:
- response to oxidative stress
- Gene Ontology Molecular Function:
- glutathione peroxidase activity
- Gene Ontology Cellular Component:
- extracellular region
- Keywords:
- Complete proteome
Oxidoreductase
Peroxidase
Polymorphism
Reference proteome
Secreted
Selenocysteine
Signal