Names & Taxonomy
- Uniprot ID:
- P52961
- Entry Name:
- NAR1_HUMAN
- Status:
- reviewed
- Protein Names:
- GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 1) (ARTC1) (Mono(ADP-ribosyl)transferase 1) (CD antigen CD296)
- Gene Names:
- ART1
- Gene Names Primary:
- ART1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 327
- Sequence:
- MQMPAMMSLLLVSVGLMEALQAQSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGQRPPRCHQVFRGVHGLRFRPAGPRATVRLGGFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRLAQGPARIYLRALGKHSTYNCEYIKDKKCKSGPCHLDNSAMGQSPLSAVWSLLLLLWFLVVRAFPDGPGLL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Sarcoplasmic reticulum membrane; Lipid-anchor, GPI-anchor.
Function
- Function:
- Has ADP-ribosyltransferase activity toward GLP1R.
- Catalytic Activity:
- NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine.
- Active Site:
- ACT_SITE 247 247
- Gene Ontology Go:
- anchored component of membrane
cell surface
integral component of plasma membrane
plasma membrane
sarcoplasmic reticulum membrane
NAD(P)+-protein-arginine ADP-ribosyltransferase activity
NAD+ ADP-ribosyltransferase activity
innate immune response
protein ADP-ribosylation - Gene Ontology Biological Process:
- innate immune response
protein ADP-ribosylation - Gene Ontology Molecular Function:
- NAD(P)+-protein-arginine ADP-ribosyltransferase activity
NAD+ ADP-ribosyltransferase activity - Gene Ontology Cellular Component:
- anchored component of membrane
cell surface
integral component of plasma membrane
plasma membrane
sarcoplasmic reticulum membrane - Keywords:
- Complete proteome
Disulfide bond
GPI-anchor
Glycoprotein
Glycosyltransferase
Lipoprotein
Membrane
NAD
NADP
Polymorphism
Reference proteome
Sarcoplasmic reticulum
Signal
Transferase