Names & Taxonomy
- Uniprot ID:
- P49913
- Entry Name:
- CAMP_HUMAN
- Status:
- reviewed
- Protein Names:
- Cathelicidin antimicrobial peptide (18 kDa cationic antimicrobial protein) (CAP-18) (hCAP-18) [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]
- Gene Names:
- CAMP CAP18 FALL39 HSD26
- Gene Names Orf:
- HSD26
- Gene Names Primary:
- CAMP
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 170
- Sequence:
- MKTQRDGHSLGRWSLVLLLLGLVMPLAIIAQVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKRFALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
- Gene Ontology Go:
- cell wall
extracellular exosome
extracellular region
extracellular space
intracellular
specific granule
antibacterial humoral response
antifungal humoral response
cell redox homeostasis
chronic inflammatory response
defense response to bacterium
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
innate immune response
innate immune response in mucosa
killing by host of symbiont cells
negative regulation of growth of symbiont on or near host surface
positive regulation of interleukin-8 secretion
response to yeast - Gene Ontology Biological Process:
- antibacterial humoral response
antifungal humoral response
cell redox homeostasis
chronic inflammatory response
defense response to bacterium
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
innate immune response
innate immune response in mucosa
killing by host of symbiont cells
negative regulation of growth of symbiont on or near host surface
positive regulation of interleukin-8 secretion
response to yeast - Gene Ontology Cellular Component:
- cell wall
extracellular exosome
extracellular region
extracellular space
intracellular
specific granule - Keywords:
- 3D-structure
Antibiotic
Antimicrobial
Cleavage on pair of basic residues
Complete proteome
Direct protein sequencing
Disulfide bond
Reference proteome
Secreted
Signal - Interacts With:
- P08069