Names & Taxonomy
- Uniprot ID:
- P46777
- Entry Name:
- RL5_HUMAN
- Status:
- reviewed
- Protein Names:
- 60S ribosomal protein L5
- Gene Names:
- RPL5 MSTP030
- Gene Names Orf:
- MSTP030
- Gene Names Primary:
- RPL5
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 297
- Sequence:
- MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNSVTPDMMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm
Function
- Function:
- Required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA.
- Gene Ontology Go:
- cytoplasm
cytosol
cytosolic large ribosomal subunit
extracellular exosome
focal adhesion
intracellular ribonucleoprotein complex
membrane
nucleolus
nucleus
5S rRNA binding
poly(A) RNA binding
RNA binding
structural constituent of ribosome
cellular nitrogen compound metabolic process
cellular protein metabolic process
gene expression
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
ribosomal large subunit assembly
ribosomal large subunit biogenesis
rRNA processing
selenium compound metabolic process
selenocysteine metabolic process
small molecule metabolic process
SRP-dependent cotranslational protein targeting to membrane
translation
translational elongation
translational initiation
translational termination
viral life cycle
viral process
viral transcription - Gene Ontology Biological Process:
- cellular nitrogen compound metabolic process
cellular protein metabolic process
gene expression
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
ribosomal large subunit assembly
ribosomal large subunit biogenesis
rRNA processing
selenium compound metabolic process
selenocysteine metabolic process
small molecule metabolic process
SRP-dependent cotranslational protein targeting to membrane
translation
translational elongation
translational initiation
translational termination
viral life cycle
viral process
viral transcription - Gene Ontology Molecular Function:
- 5S rRNA binding
poly(A) RNA binding
RNA binding
structural constituent of ribosome - Gene Ontology Cellular Component:
- cytoplasm
cytosol
cytosolic large ribosomal subunit
extracellular exosome
focal adhesion
intracellular ribonucleoprotein complex
membrane
nucleolus
nucleus - Keywords:
- 3D-structure
Acetylation
Complete proteome
Cytoplasm
Diamond-Blackfan anemia
Direct protein sequencing
Disease mutation
Nucleus
Phosphoprotein
Polymorphism
RNA-binding
Reference proteome
Ribonucleoprotein
Ribosomal protein
rRNA-binding - Interacts With:
- P43146; Q63155; Q00987