Names & Taxonomy
- Uniprot ID:
- P35243
- Entry Name:
- RECO_HUMAN
- Status:
- reviewed
- Protein Names:
- Recoverin (Cancer-associated retinopathy protein) (Protein CAR)
- Gene Names:
- RCVRN RCV1
- Gene Names Primary:
- RCVRN
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 200
- Sequence:
- MGNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQFEPQKVKEKMKNA
- Proteomes:
- UP000005640
Function
- Function:
- Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
- Gene Ontology Go:
- calcium ion binding
calcium sensitive guanylate cyclase activator activity
phototransduction, visible light
positive regulation of guanylate cyclase activity
regulation of calcium ion transport
regulation of rhodopsin mediated signaling pathway
rhodopsin mediated signaling pathway
signal transduction
visual perception - Gene Ontology Biological Process:
- phototransduction, visible light
positive regulation of guanylate cyclase activity
regulation of calcium ion transport
regulation of rhodopsin mediated signaling pathway
rhodopsin mediated signaling pathway
signal transduction
visual perception - Gene Ontology Molecular Function:
- calcium ion binding
calcium sensitive guanylate cyclase activator activity - Keywords:
- 3D-structure
Calcium
Complete proteome
Direct protein sequencing
Lipoprotein
Metal-binding
Myristate
Reference proteome
Repeat
Sensory transduction
Vision