Names & Taxonomy

Uniprot ID:
P35243
Entry Name:
RECO_HUMAN
Status:
reviewed
Protein Names:
Recoverin (Cancer-associated retinopathy protein) (Protein CAR)
Gene Names:
RCVRN RCV1
Gene Names Primary:
RCVRN
Organism:
Homo sapiens (Human)

Structure

Length:
200
Sequence:
MGNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQFEPQKVKEKMKNA
Proteomes:
UP000005640

Function

Function:
Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
Gene Ontology Go:
calcium ion binding
calcium sensitive guanylate cyclase activator activity
phototransduction, visible light
positive regulation of guanylate cyclase activity
regulation of calcium ion transport
regulation of rhodopsin mediated signaling pathway
rhodopsin mediated signaling pathway
signal transduction
visual perception
Gene Ontology Biological Process:
phototransduction, visible light
positive regulation of guanylate cyclase activity
regulation of calcium ion transport
regulation of rhodopsin mediated signaling pathway
rhodopsin mediated signaling pathway
signal transduction
visual perception
Gene Ontology Molecular Function:
calcium ion binding
calcium sensitive guanylate cyclase activator activity
Keywords:
3D-structure
Calcium
Complete proteome
Direct protein sequencing
Lipoprotein
Metal-binding
Myristate
Reference proteome
Repeat
Sensory transduction
Vision

Publication

PubMed ID:
1387789 8500558 1388144 8912538 14702039 21697133 15489334 1999465