Names & Taxonomy
- Uniprot ID:
- P34741
- Entry Name:
- SDC2_HUMAN
- Status:
- reviewed
- Protein Names:
- Syndecan-2 (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG) (CD antigen CD362)
- Gene Names:
- SDC2 HSPG1
- Gene Names Primary:
- SDC2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 201
- Sequence:
- MRRAWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Single-pass type I membrane protein.
Function
- Function:
- Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).
- Cross Reference Drug Bank:
- DB00020
- Gene Ontology Go:
- cell surface
Golgi lumen
integral component of membrane
lysosomal lumen
neuronal cell body
plasma membrane
synapse
PDZ domain binding
axon guidance
bioluminescence
carbohydrate metabolic process
cell migration
chondroitin sulfate metabolic process
dendrite morphogenesis
ephrin receptor signaling pathway
extracellular matrix organization
fat-soluble vitamin metabolic process
glycosaminoglycan biosynthetic process
glycosaminoglycan catabolic process
glycosaminoglycan metabolic process
phototransduction, visible light
regulation of dendrite morphogenesis
response to caffeine
response to hypoxia
retinoid metabolic process
small molecule metabolic process
vitamin metabolic process
wound healing - Gene Ontology Biological Process:
- axon guidance
bioluminescence
carbohydrate metabolic process
cell migration
chondroitin sulfate metabolic process
dendrite morphogenesis
ephrin receptor signaling pathway
extracellular matrix organization
fat-soluble vitamin metabolic process
glycosaminoglycan biosynthetic process
glycosaminoglycan catabolic process
glycosaminoglycan metabolic process
phototransduction, visible light
regulation of dendrite morphogenesis
response to caffeine
response to hypoxia
retinoid metabolic process
small molecule metabolic process
vitamin metabolic process
wound healing - Gene Ontology Molecular Function:
- PDZ domain binding
- Gene Ontology Cellular Component:
- cell surface
Golgi lumen
integral component of membrane
lysosomal lumen
neuronal cell body
plasma membrane
synapse - Keywords:
- Complete proteome
Differentiation
Glycoprotein
Heparan sulfate
Luminescence
Membrane
Neurogenesis
Phosphoprotein
Photoprotein
Polymorphism
Proteoglycan
Reference proteome
Signal
Transmembrane
Transmembrane helix - Interacts With:
- O14936; P21359