Names & Taxonomy
- Uniprot ID:
- P23763
- Entry Name:
- VAMP1_HUMAN
- Status:
- reviewed
- Protein Names:
- Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1)
- Gene Names:
- VAMP1 SYB1
- Gene Names Primary:
- VAMP1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 118
- Sequence:
- MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Function
- Function:
- Involved in the targeting and/or fusion of transport vesicles to their target membrane.
- Cross Reference Drug Bank:
- DB00042
- Gene Ontology Go:
- cell junction
cell surface
cytosol
integral component of plasma membrane
mitochondrial outer membrane
specific granule membrane
synaptic vesicle membrane
terminal bouton
tertiary granule membrane
SNAP receptor activity
SNARE binding
SNARE complex assembly
vesicle fusion - Gene Ontology Biological Process:
- SNARE complex assembly
vesicle fusion - Gene Ontology Molecular Function:
- SNAP receptor activity
SNARE binding - Gene Ontology Cellular Component:
- cell junction
cell surface
cytosol
integral component of plasma membrane
mitochondrial outer membrane
specific granule membrane
synaptic vesicle membrane
terminal bouton
tertiary granule membrane - Keywords:
- Alternative splicing
Cell junction
Coiled coil
Complete proteome
Cytoplasmic vesicle
Membrane
Mitochondrion
Mitochondrion outer membrane
Neurodegeneration
Phosphoprotein
Reference proteome
Synapse
Synaptosome
Transmembrane
Transmembrane helix - Interacts With:
- Q8N6L0; O95721; Q12846