Names & Taxonomy
- Uniprot ID:
- P20674
- Entry Name:
- COX5A_HUMAN
- Status:
- reviewed
- Protein Names:
- Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)
- Gene Names:
- COX5A
- Gene Names Primary:
- COX5A
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 150
- Sequence:
- MLGAALRRCAVAATTRADPRGLLHSARTPGPAVAIQSVRCYSHGSQETDEEFDARWVTYFNKPDIDAWELRKGINTLVTYDMVPEPKIIDAALRACRRLNDFASTVRILEVVKDKAGPHKEIYPYVIQELRPTLNELGISTPEELGLDKV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Mitochondrion inner membrane.
Function
- Function:
- This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
- Cross Reference Drug Bank:
- DB02659
- Gene Ontology Go:
- extracellular exosome
mitochondrial inner membrane
mitochondrial respiratory chain complex IV
myelin sheath
cytochrome-c oxidase activity
electron carrier activity
metal ion binding
cellular metabolic process
gene expression
mitochondrial electron transport, cytochrome c to oxygen
respiratory electron transport chain
small molecule metabolic process
transcription initiation from RNA polymerase II promoter - Gene Ontology Biological Process:
- cellular metabolic process
gene expression
mitochondrial electron transport, cytochrome c to oxygen
respiratory electron transport chain
small molecule metabolic process
transcription initiation from RNA polymerase II promoter - Gene Ontology Molecular Function:
- cytochrome-c oxidase activity
electron carrier activity
metal ion binding - Gene Ontology Cellular Component:
- extracellular exosome
mitochondrial inner membrane
mitochondrial respiratory chain complex IV
myelin sheath - Keywords:
- Acetylation
Complete proteome
Direct protein sequencing
Heme
Iron
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
Phosphoprotein
Reference proteome
Transit peptide - Interacts With:
- Q96B26; Q15323; Q6A162