Names & Taxonomy

Uniprot ID:
P20674
Entry Name:
COX5A_HUMAN
Status:
reviewed
Protein Names:
Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)
Gene Names:
COX5A
Gene Names Primary:
COX5A
Organism:
Homo sapiens (Human)

Structure

Length:
150
Sequence:
MLGAALRRCAVAATTRADPRGLLHSARTPGPAVAIQSVRCYSHGSQETDEEFDARWVTYFNKPDIDAWELRKGINTLVTYDMVPEPKIIDAALRACRRLNDFASTVRILEVVKDKAGPHKEIYPYVIQELRPTLNELGISTPEELGLDKV
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Mitochondrion inner membrane.

Function

Function:
This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Cross Reference Drug Bank:
DB02659
Gene Ontology Go:
extracellular exosome
mitochondrial inner membrane
mitochondrial respiratory chain complex IV
myelin sheath
cytochrome-c oxidase activity
electron carrier activity
metal ion binding
cellular metabolic process
gene expression
mitochondrial electron transport, cytochrome c to oxygen
respiratory electron transport chain
small molecule metabolic process
transcription initiation from RNA polymerase II promoter
Gene Ontology Biological Process:
cellular metabolic process
gene expression
mitochondrial electron transport, cytochrome c to oxygen
respiratory electron transport chain
small molecule metabolic process
transcription initiation from RNA polymerase II promoter
Gene Ontology Molecular Function:
cytochrome-c oxidase activity
electron carrier activity
metal ion binding
Gene Ontology Cellular Component:
extracellular exosome
mitochondrial inner membrane
mitochondrial respiratory chain complex IV
myelin sheath
Keywords:
Acetylation
Complete proteome
Direct protein sequencing
Heme
Iron
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
Phosphoprotein
Reference proteome
Transit peptide
Interacts With:
Q96B26; Q15323; Q6A162

Publication

PubMed ID:
2853101 18197981 16572171 15489334 8313870 7498159 21269460 24275569 25944712