Names & Taxonomy
- Uniprot ID:
- P17538
- Entry Name:
- CTRB1_HUMAN
- Status:
- reviewed
- Protein Names:
- Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C]
- Gene Names:
- CTRB1 CTRB
- Gene Names Primary:
- CTRB1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 263
- Sequence:
- MAFLWLLSCWALLGTTFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQKILAAN
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted, extracellular space.
Function
- Catalytic Activity:
- Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
- Active Site:
- ACT_SITE 75 75 Charge relay system.
- Cross Reference Drug Bank:
- DB06692
- Gene Ontology Go:
- extracellular region
extracellular space
serine-type endopeptidase activity
cobalamin metabolic process
digestion
extracellular matrix disassembly
extracellular matrix organization
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process - Gene Ontology Biological Process:
- cobalamin metabolic process
digestion
extracellular matrix disassembly
extracellular matrix organization
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process - Gene Ontology Molecular Function:
- serine-type endopeptidase activity
- Gene Ontology Cellular Component:
- extracellular region
extracellular space - Keywords:
- Complete proteome
Digestion
Disulfide bond
Hydrolase
Phosphoprotein
Polymorphism
Protease
Reference proteome
Secreted
Serine protease
Signal
Zymogen