Names & Taxonomy
- Uniprot ID:
- P15086
- Entry Name:
- CBPB1_HUMAN
- Status:
- reviewed
- Protein Names:
- Carboxypeptidase B (EC 3.4.17.2) (Pancreas-specific protein) (PASP)
- Gene Names:
- CPB1 CPB PCPB
- Gene Names Primary:
- CPB1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 417
- Sequence:
- MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted
Function
- Catalytic Activity:
- Preferential release of a C-terminal lysine or arginine amino acid.
- Cofactor:
- COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Active Site:
- ACT_SITE 378 378 Proton donor/acceptor.
- Gene Ontology Go:
- extracellular space
carboxypeptidase activity
metallocarboxypeptidase activity
zinc ion binding - Gene Ontology Molecular Function:
- carboxypeptidase activity
metallocarboxypeptidase activity
zinc ion binding - Gene Ontology Cellular Component:
- extracellular space
- Keywords:
- 3D-structure
Carboxypeptidase
Complete proteome
Direct protein sequencing
Disulfide bond
Hydrolase
Metal-binding
Metalloprotease
Polymorphism
Protease
Reference proteome
Secreted
Signal
Zinc
Zymogen