Names & Taxonomy

Uniprot ID:
P14854
Entry Name:
CX6B1_HUMAN
Status:
reviewed
Protein Names:
Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1)
Gene Names:
COX6B1 COX6B
Gene Names Primary:
COX6B1
Organism:
Homo sapiens (Human)

Structure

Length:
86
Sequence:
MAEDMETKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTAKGGDISVCEWYQRVYQSLCPTSWVTDWDEQRAEGTFPGKI
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Mitochondrion intermembrane space

Function

Function:
Connects the two COX monomers into the physiological dimeric form.
Cross Reference Drug Bank:
DB02659
Gene Ontology Go:
mitochondrial inner membrane
mitochondrial intermembrane space
mitochondrion
cytochrome-c oxidase activity
cellular metabolic process
gene expression
hydrogen ion transmembrane transport
respiratory electron transport chain
small molecule metabolic process
substantia nigra development
transcription initiation from RNA polymerase II promoter
Gene Ontology Biological Process:
cellular metabolic process
gene expression
hydrogen ion transmembrane transport
respiratory electron transport chain
small molecule metabolic process
substantia nigra development
transcription initiation from RNA polymerase II promoter
Gene Ontology Molecular Function:
cytochrome-c oxidase activity
Gene Ontology Cellular Component:
mitochondrial inner membrane
mitochondrial intermembrane space
mitochondrion
Keywords:
Acetylation
Complete proteome
Disease mutation
Disulfide bond
Mitochondrion
Reference proteome

Publication

PubMed ID:
2537962 2172092 1651883 14702039 15057824 15489334 1647217 21269460 22814378 24275569 25944712 18499082