Names & Taxonomy
- Uniprot ID:
- P13797
- Entry Name:
- PLST_HUMAN
- Status:
- reviewed
- Protein Names:
- Plastin-3 (T-plastin)
- Gene Names:
- PLS3
- Gene Names Primary:
- PLS3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 630
- Sequence:
- MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm.
Function
- Function:
- Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. May play a role in the regulation of bone development.
- Gene Ontology Go:
- cytoplasm
stereocilium
calcium ion binding
auditory receptor cell differentiation
bone development - Gene Ontology Biological Process:
- auditory receptor cell differentiation
bone development - Gene Ontology Molecular Function:
- calcium ion binding
- Gene Ontology Cellular Component:
- cytoplasm
stereocilium - Keywords:
- 3D-structure
Acetylation
Actin-binding
Alternative splicing
Calcium
Complete proteome
Cytoplasm
Direct protein sequencing
Disease mutation
Isopeptide bond
Metal-binding
Phosphoprotein
Polymorphism
Reference proteome
Repeat
Ubl conjugation