Names & Taxonomy
- Uniprot ID:
- P13688
- Entry Name:
- CEAM1_HUMAN
- Status:
- reviewed
- Protein Names:
- Carcinoembryonic antigen-related cell adhesion molecule 1 (Biliary glycoprotein 1) (BGP-1) (CD antigen CD66a)
- Gene Names:
- CEACAM1 BGP BGP1
- Gene Names Primary:
- CEACAM1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 526
- Sequence:
- MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHTQDHSNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKKQ
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Isoform 1: Cell membrane; Single-pass type I membrane protein.; Isoform 2: Secreted.; Isoform 3: Secreted.; Isoform 4: Secreted.; Isoform 5: Cell membrane; Single-pass type I membrane protein.; Isoform 6: Cell membrane; Single-pass type I membrane protein.; Isoform 7: Cell membrane; Single-pass type I membrane protein.; Isoform 8: Cell membrane; Single-pass type I membrane protein. Note=Localizes to sites of cell-cell contact.
Function
- Cross Reference Drug Bank:
- DB00113
- Gene Ontology Go:
- extracellular exosome
integral component of membrane
integral component of plasma membrane
membrane
plasma membrane
protein homodimerization activity
angiogenesis
blood coagulation
cell migration
homophilic cell adhesion via plasma membrane adhesion molecules
integrin-mediated signaling pathway
leukocyte migration - Gene Ontology Biological Process:
- angiogenesis
blood coagulation
cell migration
homophilic cell adhesion via plasma membrane adhesion molecules
integrin-mediated signaling pathway
leukocyte migration - Gene Ontology Molecular Function:
- protein homodimerization activity
- Gene Ontology Cellular Component:
- extracellular exosome
integral component of membrane
integral component of plasma membrane
membrane
plasma membrane - Keywords:
- 3D-structure
Alternative splicing
Cell membrane
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Membrane
Polymorphism
Pyrrolidone carboxylic acid
Reference proteome
Repeat
Secreted
Signal
Transmembrane
Transmembrane helix - Interacts With:
- Q16568; P40199; Q8GH87