Names & Taxonomy

Uniprot ID:
P13688
Entry Name:
CEAM1_HUMAN
Status:
reviewed
Protein Names:
Carcinoembryonic antigen-related cell adhesion molecule 1 (Biliary glycoprotein 1) (BGP-1) (CD antigen CD66a)
Gene Names:
CEACAM1 BGP BGP1
Gene Names Primary:
CEACAM1
Organism:
Homo sapiens (Human)

Structure

Length:
526
Sequence:
MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHTQDHSNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKKQ
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein.; Isoform 2: Secreted.; Isoform 3: Secreted.; Isoform 4: Secreted.; Isoform 5: Cell membrane; Single-pass type I membrane protein.; Isoform 6: Cell membrane; Single-pass type I membrane protein.; Isoform 7: Cell membrane; Single-pass type I membrane protein.; Isoform 8: Cell membrane; Single-pass type I membrane protein. Note=Localizes to sites of cell-cell contact.

Function

Cross Reference Drug Bank:
DB00113
Gene Ontology Go:
extracellular exosome
integral component of membrane
integral component of plasma membrane
membrane
plasma membrane
protein homodimerization activity
angiogenesis
blood coagulation
cell migration
homophilic cell adhesion via plasma membrane adhesion molecules
integrin-mediated signaling pathway
leukocyte migration
Gene Ontology Biological Process:
angiogenesis
blood coagulation
cell migration
homophilic cell adhesion via plasma membrane adhesion molecules
integrin-mediated signaling pathway
leukocyte migration
Gene Ontology Molecular Function:
protein homodimerization activity
Gene Ontology Cellular Component:
extracellular exosome
integral component of membrane
integral component of plasma membrane
membrane
plasma membrane
Keywords:
3D-structure
Alternative splicing
Cell membrane
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Membrane
Polymorphism
Pyrrolidone carboxylic acid
Reference proteome
Repeat
Secreted
Signal
Transmembrane
Transmembrane helix
Interacts With:
Q16568; P40199; Q8GH87

Publication

PubMed ID:
2457922 2537311 2025273 8423792 8018919 15057824 15489334 8055923 7628460 11501563 16335952 19159218 21269460 24275569 16929097