Names & Taxonomy
- Uniprot ID:
- P0DMS8
- Entry Name:
- AA3R_HUMAN
- Status:
- reviewed
- Protein Names:
- Adenosine receptor A3
- Gene Names:
- ADORA3
- Gene Names Primary:
- ADORA3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 318
- Sequence:
- MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
Function
- Function:
- Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.
- Cross Reference Drug Bank:
- DB00640 DB01223 DB00824
- Gene Ontology Go:
- integral component of membrane
plasma membrane
G-protein coupled adenosine receptor activity - Gene Ontology Molecular Function:
- G-protein coupled adenosine receptor activity
- Gene Ontology Cellular Component:
- integral component of membrane
plasma membrane - Keywords:
- 3D-structure
Alternative splicing
Cell membrane
Complete proteome
Disulfide bond
G-protein coupled receptor
Glycoprotein
Lipoprotein
Membrane
Palmitate
Phosphoprotein
Polymorphism
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix