Names & Taxonomy
- Uniprot ID:
- P08574
- Entry Name:
- CY1_HUMAN
- Status:
- reviewed
- Protein Names:
- Cytochrome c1, heme protein, mitochondrial (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1)
- Gene Names:
- CYC1
- Gene Names Primary:
- CYC1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 325
- Sequence:
- MAAAAASLRGVVLGPRGAGLPGARARGLLCSARPGQLPLRTPQAVALSSKSGLSRGRKVMLSALGMLAAGGAGLAMALHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCASCHSMDFVAYRHLVGVCYTEDEAKELAAEVEVQDGPNEDGEMFMRPGKLFDYFPKPYPNSEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIAMAPPIYTDVLEFDDGTPATMSQIAKDVCTFLRWASEPEHDHRKRMGLKMLMMMALLVPLVYTIKRHKWSVLKSRKLAYRPPK
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Function
- Function:
- This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.
- Gene Ontology Go:
- integral component of membrane
membrane
mitochondrial inner membrane
mitochondrion
nucleus
respiratory chain
electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
heme binding
metal ion binding
cellular metabolic process
respiratory electron transport chain
response to glucagon
small molecule metabolic process - Gene Ontology Biological Process:
- cellular metabolic process
respiratory electron transport chain
response to glucagon
small molecule metabolic process - Gene Ontology Molecular Function:
- electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
heme binding
metal ion binding - Gene Ontology Cellular Component:
- integral component of membrane
membrane
mitochondrial inner membrane
mitochondrion
nucleus
respiratory chain - Keywords:
- Complete proteome
Disease mutation
Electron transport
Heme
Iron
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
Polymorphism
Reference proteome
Respiratory chain
Transit peptide
Transmembrane
Transmembrane helix
Transport