Names & Taxonomy
- Uniprot ID:
- P05452
- Entry Name:
- TETN_HUMAN
- Status:
- reviewed
- Protein Names:
- Tetranectin (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein)
- Gene Names:
- CLEC3B TNA
- Gene Names Primary:
- CLEC3B
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 202
- Sequence:
- MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
- Cross Reference Drug Bank:
- DB00031
- Gene Ontology Go:
- cytoplasm
extracellular exosome
extracellular region
extracellular space
granular component
calcium ion binding
carbohydrate binding
heparin binding
kringle domain binding
bone mineralization
cellular response to organic substance
cellular response to transforming growth factor beta stimulus
ossification
positive regulation of plasminogen activation - Gene Ontology Biological Process:
- bone mineralization
cellular response to organic substance
cellular response to transforming growth factor beta stimulus
ossification
positive regulation of plasminogen activation - Gene Ontology Molecular Function:
- calcium ion binding
carbohydrate binding
heparin binding
kringle domain binding - Gene Ontology Cellular Component:
- cytoplasm
extracellular exosome
extracellular region
extracellular space
granular component - Keywords:
- 3D-structure
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Lectin
Polymorphism
Reference proteome
Secreted
Signal