Names & Taxonomy

Uniprot ID:
P05452
Entry Name:
TETN_HUMAN
Status:
reviewed
Protein Names:
Tetranectin (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein)
Gene Names:
CLEC3B TNA
Gene Names Primary:
CLEC3B
Organism:
Homo sapiens (Human)

Structure

Length:
202
Sequence:
MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Secreted.

Function

Function:
Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
Cross Reference Drug Bank:
DB00031
Gene Ontology Go:
cytoplasm
extracellular exosome
extracellular region
extracellular space
granular component
calcium ion binding
carbohydrate binding
heparin binding
kringle domain binding
bone mineralization
cellular response to organic substance
cellular response to transforming growth factor beta stimulus
ossification
positive regulation of plasminogen activation
Gene Ontology Biological Process:
bone mineralization
cellular response to organic substance
cellular response to transforming growth factor beta stimulus
ossification
positive regulation of plasminogen activation
Gene Ontology Molecular Function:
calcium ion binding
carbohydrate binding
heparin binding
kringle domain binding
Gene Ontology Cellular Component:
cytoplasm
extracellular exosome
extracellular region
extracellular space
granular component
Keywords:
3D-structure
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Lectin
Polymorphism
Reference proteome
Secreted
Signal

Publication

PubMed ID:
1354271 1511740 16641997 15489334 3427041 10614823 24275569 9256258 9757090