Names & Taxonomy

Uniprot ID:
P01859
Entry Name:
IGHG2_HUMAN
Status:
reviewed
Protein Names:
Ig gamma-2 chain C region
Gene Names:
IGHG2
Gene Names Primary:
IGHG2
Organism:
Homo sapiens (Human)

Structure

Length:
326
Sequence:
ASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDISVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Secreted.

Function

Gene Ontology Go:
blood microparticle
external side of plasma membrane
extracellular exosome
extracellular region
extracellular space
immunoglobulin complex, circulating
antigen binding
immunoglobulin receptor binding
B cell receptor signaling pathway
complement activation
complement activation, classical pathway
defense response to bacterium
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
phagocytosis, engulfment
phagocytosis, recognition
positive regulation of B cell activation
Gene Ontology Biological Process:
B cell receptor signaling pathway
complement activation
complement activation, classical pathway
defense response to bacterium
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
phagocytosis, engulfment
phagocytosis, recognition
positive regulation of B cell activation
Gene Ontology Molecular Function:
antigen binding
immunoglobulin receptor binding
Gene Ontology Cellular Component:
blood microparticle
external side of plasma membrane
extracellular exosome
extracellular region
extracellular space
immunoglobulin complex, circulating
Keywords:
3D-structure
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin C region
Immunoglobulin domain
Reference proteome
Secreted
Interacts With:
Q28109

Publication

PubMed ID:
12508121 6804948 6811139 6329676 6774012 113060 118920 7737190 4940472 5782707 15084671 19159218 19139490