Names & Taxonomy

Uniprot ID:
O94832
Entry Name:
MYO1D_HUMAN
Status:
reviewed
Protein Names:
Unconventional myosin-Id
Gene Names:
MYO1D KIAA0727
Gene Names Primary:
MYO1D
Organism:
Homo sapiens (Human)

Structure

Length:
1006
Sequence:
MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSIIAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN
Proteomes:
UP000005640

Function

Function:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
Gene Ontology Go:
apical dendrite
axolemma
axon
basolateral plasma membrane
brush border
cytoplasmic vesicle
endosome
extracellular exosome
myelin sheath
myosin complex
neuron projection
neuronal cell body
plasma membrane raft
smooth endoplasmic reticulum
actin filament binding
actin-dependent ATPase activity
ATP binding
calmodulin binding
microfilament motor activity
protein domain specific binding
cellular localization
early endosome to recycling endosome transport
negative regulation of phosphatase activity
Gene Ontology Biological Process:
cellular localization
early endosome to recycling endosome transport
negative regulation of phosphatase activity
Gene Ontology Molecular Function:
actin-dependent ATPase activity
actin filament binding
ATP binding
calmodulin binding
microfilament motor activity
protein domain specific binding
Gene Ontology Cellular Component:
apical dendrite
axolemma
axon
basolateral plasma membrane
brush border
cytoplasmic vesicle
endosome
extracellular exosome
myelin sheath
myosin complex
neuronal cell body
neuron projection
plasma membrane raft
smooth endoplasmic reticulum
Keywords:
ATP-binding
Acetylation
Actin-binding
Calmodulin-binding
Complete proteome
Direct protein sequencing
Motor protein
Myosin
Nucleotide-binding
Phosphoprotein
Polymorphism
Reference proteome
Repeat

Publication

PubMed ID:
9872452 15489334 18669648 21269460