Names & Taxonomy
- Uniprot ID:
- O60551
- Entry Name:
- NMT2_HUMAN
- Status:
- reviewed
- Protein Names:
- Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Peptide N-myristoyltransferase 2) (Type II N-myristoyltransferase)
- Gene Names:
- NMT2
- Gene Names Primary:
- NMT2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 498
- Sequence:
- MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGYLGAKKKKKKQKRKKEKPNSGGTKSDSASDSQEIKIQQPSKNPSVPMQKLQDIQRAMELLSACQGPARNIDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm
Function
- Function:
- Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
- Catalytic Activity:
- Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.
- Gene Ontology Go:
- cytoplasm
cytosol
extrinsic component of membrane
Golgi apparatus
plasma membrane
glycylpeptide N-tetradecanoyltransferase activity
intracellular transport of virus
N-terminal peptidyl-glycine N-myristoylation
phototransduction, visible light
regulation of rhodopsin mediated signaling pathway
rhodopsin mediated signaling pathway
viral process
viral protein processing
virion assembly - Gene Ontology Biological Process:
- intracellular transport of virus
N-terminal peptidyl-glycine N-myristoylation
phototransduction, visible light
regulation of rhodopsin mediated signaling pathway
rhodopsin mediated signaling pathway
viral process
viral protein processing
virion assembly - Gene Ontology Molecular Function:
- glycylpeptide N-tetradecanoyltransferase activity
- Gene Ontology Cellular Component:
- cytoplasm
cytosol
extrinsic component of membrane
Golgi apparatus
plasma membrane - Keywords:
- 3D-structure
Acyltransferase
Complete proteome
Cytoplasm
Membrane
Phosphoprotein
Reference proteome
Transferase