Names & Taxonomy
- Uniprot ID:
- O43896
- Entry Name:
- KIF1C_HUMAN
- Status:
- reviewed
- Protein Names:
- Kinesin-like protein KIF1C
- Gene Names:
- KIF1C KIAA0706
- Gene Names Primary:
- KIF1C
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1103
- Sequence:
- MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINEDPNARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGALPAVSSPPAPVSPSSPTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQVDMDIKLTGQFIREQHCLFRSIPQPDGEVVVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGDDSDKRSCEESWRLISSLREQLPPTTVQTIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPDGPGDAWRAVARDVWDTVGEEEGGGAGSGGGSEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRELQALRDRMLRMERVIPLAQDHEDENEEGGEVPWAPPEGSEAAEEAAPSDRMPSARPPSPPLSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGSGGRGGGLRRPPARFVPPHDCKLRFPFKSNPQHRESWPGMGSGEAPTPLQPPEEVTPHPATPARRPPSPRRSHHPRRNSLDGGGRSRGAGSAQPEPQHFQPKKHNSYPQPPQPYPAQRPPGPRYPPYTTPPRMRRQRSAPDLKESGAAV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm, cytoskeleton
Function
- Function:
- Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.
- Gene Ontology Go:
- endoplasmic reticulum
Golgi apparatus
kinesin complex
microtubule
ATP binding
ATPase activity
microtubule motor activity
motor activity
poly(A) RNA binding
cytoskeleton-dependent intracellular transport
microtubule-based movement
retrograde vesicle-mediated transport, Golgi to ER - Gene Ontology Biological Process:
- cytoskeleton-dependent intracellular transport
microtubule-based movement
retrograde vesicle-mediated transport, Golgi to ER - Gene Ontology Molecular Function:
- ATPase activity
ATP binding
microtubule motor activity
motor activity
poly(A) RNA binding - Gene Ontology Cellular Component:
- endoplasmic reticulum
Golgi apparatus
kinesin complex
microtubule - Keywords:
- 3D-structure
ATP-binding
Coiled coil
Complete proteome
Cytoplasm
Cytoskeleton
Disease mutation
Microtubule
Motor protein
Neurodegeneration
Nucleotide-binding
Phosphoprotein
Reference proteome - Interacts With:
- A0JNT9