Names & Taxonomy
- Uniprot ID:
- O15511
- Entry Name:
- ARPC5_HUMAN
- Status:
- reviewed
- Protein Names:
- Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC)
- Gene Names:
- ARPC5 ARC16
- Gene Names Primary:
- ARPC5
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 151
- Sequence:
- MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm, cytoskeleton
Function
- Function:
- Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
- Gene Ontology Go:
- actin cytoskeleton
Arp2/3 protein complex
cell projection
cytoplasm
cytosol
extracellular exosome
focal adhesion
structural constituent of cytoskeleton
actin cytoskeleton organization
Arp2/3 complex-mediated actin nucleation
axon guidance
cell migration
ephrin receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
movement of cell or subcellular component
small GTPase mediated signal transduction - Gene Ontology Biological Process:
- actin cytoskeleton organization
Arp2/3 complex-mediated actin nucleation
axon guidance
cell migration
ephrin receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
movement of cell or subcellular component
small GTPase mediated signal transduction - Gene Ontology Molecular Function:
- structural constituent of cytoskeleton
- Gene Ontology Cellular Component:
- actin cytoskeleton
Arp2/3 protein complex
cell projection
cytoplasm
cytosol
extracellular exosome
focal adhesion - Keywords:
- Acetylation
Actin-binding
Alternative splicing
Cell projection
Complete proteome
Cytoplasm
Cytoskeleton
Direct protein sequencing
Reference proteome
Ubl conjugation