Names & Taxonomy
- Uniprot ID:
- K4RH61
- Entry Name:
- K4RH61_HUMAN
- Status:
- unreviewed
- Protein Names:
- Matrix metalloproteinase 14 (Membrane-inserted)
- Gene Names:
- MMP14
- Gene Names Primary:
- MMP14
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 582
- Sequence:
- MSPAPRPPRCLLLPLLRLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
Function
- Active Site:
- ACT_SITE 240 240
- Gene Ontology Go:
- extracellular matrix
integral component of membrane
calcium ion binding
metalloendopeptidase activity
zinc ion binding
positive regulation of cell growth
positive regulation of cell migration - Gene Ontology Biological Process:
- positive regulation of cell growth
positive regulation of cell migration - Gene Ontology Molecular Function:
- calcium ion binding
metalloendopeptidase activity
zinc ion binding - Gene Ontology Cellular Component:
- extracellular matrix
integral component of membrane - Keywords:
- Calcium
Disulfide bond
Hydrolase
Membrane
Metal-binding
Metalloprotease
Protease
Repeat
Signal
Transmembrane
Transmembrane helix
Zinc