Names & Taxonomy
- Uniprot ID:
- I6MBV4
- Entry Name:
- I6MBV4_HUMAN
- Status:
- unreviewed
- Protein Names:
- EBF1-PDGFRB fusion protein
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1161
- Sequence:
- MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSYLEHATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQALPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPYDNYVPSAPERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQDEPEPEPQLELQVEPEPELEQLPDSGCPAPRAEAEDSFL
Subcellular location
- Subcellular Location:
- Nucleus
Function
- Catalytic Activity:
- ATP + a -L-tyrosine = ADP + a -L-tyrosine phosphate.
- Gene Ontology Go:
- integral component of membrane
nucleus
ATP binding
DNA binding
metal ion binding
transmembrane receptor protein tyrosine kinase activity
multicellular organism development
regulation of transcription, DNA-templated
transcription, DNA-templated
transmembrane receptor protein tyrosine kinase signaling pathway - Gene Ontology Biological Process:
- multicellular organism development
regulation of transcription, DNA-templated
transcription, DNA-templated
transmembrane receptor protein tyrosine kinase signaling pathway - Gene Ontology Molecular Function:
- ATP binding
DNA binding
metal ion binding
transmembrane receptor protein tyrosine kinase activity - Gene Ontology Cellular Component:
- integral component of membrane
nucleus - Keywords:
- ATP-binding
DNA-binding
Developmental protein
Disulfide bond
Kinase
Membrane
Metal-binding
Nucleotide-binding
Nucleus
Phosphoprotein
Receptor
Transcription
Transcription regulation
Transferase
Transmembrane
Transmembrane helix
Tyrosine-protein kinase
Zinc
Zinc-finger