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Uniprot ID:: D3DRD4
Entry Name:: D3DRD4_HUMAN
Status:: unreviewed
Protein Names:: Fibroblast growth factor receptor 2 (Bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome), isoform CR... (Fibroblast growth factor receptor 2 (Bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome), isoform CRA_d)
Gene Names:: FGFR2 hCG_1811153
Gene Names Orf:: hCG_1811153
Gene Names Primary:: FGFR2
Organism:: Homo sapiens (Human)

Length:: 724
Sequence:: MGLTSTWRYGRGPGIGTVTMVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT

Catalytic Activity:: ATP + a -L-tyrosine = ADP + a -L-tyrosine phosphate.
Gene Ontology Go:: integral component of membrane
intracellular membrane-bounded organelle
nucleoplasm
ATP binding
protein tyrosine kinase activity
Gene Ontology Molecular Function:: ATP binding
protein tyrosine kinase activity
Gene Ontology Cellular Component:: integral component of membrane
intracellular membrane-bounded organelle
nucleoplasm
Keywords:: ATP-binding
Disulfide bond
Immunoglobulin domain
Kinase
Membrane
Nucleotide-binding
Receptor
Repeat
Transferase
Transmembrane
Transmembrane helix
Tyrosine-protein kinase