Names & Taxonomy

Uniprot ID:
A0A024RC29
Entry Name:
A0A024RC29_HUMAN
Status:
unreviewed
Protein Names:
Desmocollin 3, isoform CRA_b
Gene Names:
DSC3 hCG_2022649
Gene Names Orf:
hCG_2022649
Gene Names Primary:
DSC3
Organism:
Homo sapiens (Human)

Structure

Length:
896
Sequence:
MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRSADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVSKTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIEMMKGGNQTLESCRGAGHHHSLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDGLDFLNNLEPKFITLAEACTKR

Subcellular location

Subcellular Location:
Cell membrane

Function

Function:
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Gene Ontology Go:
integral component of membrane
plasma membrane
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules
Gene Ontology Biological Process:
homophilic cell adhesion via plasma membrane adhesion molecules
Gene Ontology Molecular Function:
calcium ion binding
Gene Ontology Cellular Component:
integral component of membrane
plasma membrane
Keywords:
Calcium
Cell adhesion
Cell membrane
Membrane
Repeat
Signal
Transmembrane
Transmembrane helix

Publication

PubMed ID:
11181995