Names & Taxonomy
- Uniprot ID:
- B7Z3Z4
- Entry Name:
- B7Z3Z4_HUMAN
- Status:
- unreviewed
- Protein Names:
- Beta-site APP-cleaving enzyme 1, isoform CRA_f (cDNA FLJ54693, highly similar to Beta-secretase 1 (EC 3.4.23.46))
- Gene Names:
- BACE1 hCG_37942
- Gene Names Orf:
- hCG_37942
- Gene Names Primary:
- BACE1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 401
- Sequence:
- MVPFIYLQAHFTLCSGWSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
Function
- Gene Ontology Go:
- integral component of membrane
aspartic-type endopeptidase activity - Gene Ontology Molecular Function:
- aspartic-type endopeptidase activity
- Gene Ontology Cellular Component:
- integral component of membrane
- Keywords:
- Membrane
Transmembrane
Transmembrane helix
Publication
- PubMed ID:
- 11181995