Names & Taxonomy

Uniprot ID:
B4DMK9
Entry Name:
B4DMK9_HUMAN
Status:
unreviewed
Protein Names:
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)
Organism:
Homo sapiens (Human)

Structure

Length:
486
Sequence:
MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKAAQLGFKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQSKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF

Function

Catalytic Activity:
Protein N(6)-(dihydrolipoyl)lysine + NAD(+) = protein N(6)-(lipoyl)lysine + NADH.
Cofactor:
COFACTOR: Name=FAD; Xref=ChEBI:CHEBI:57692;
Gene Ontology Go:
cell
dihydrolipoyl dehydrogenase activity
flavin adenine dinucleotide binding
cell redox homeostasis
Gene Ontology Biological Process:
cell redox homeostasis
Gene Ontology Molecular Function:
dihydrolipoyl dehydrogenase activity
flavin adenine dinucleotide binding
Gene Ontology Cellular Component:
cell
Keywords:
FAD
Flavoprotein
NAD
Oxidoreductase
Redox-active center