Names & Taxonomy
- Uniprot ID:
- B3KRQ8
- Entry Name:
- B3KRQ8_HUMAN
- Status:
- unreviewed
- Protein Names:
- DNA-directed RNA polymerase subunit beta (EC 2.7.7.6)
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 838
- Sequence:
- MWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE
Function
- Function:
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
- Catalytic Activity:
- Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
- Gene Ontology Go:
- DNA binding
DNA-directed RNA polymerase activity
ribonucleoside binding
transcription, DNA-templated - Gene Ontology Biological Process:
- transcription, DNA-templated
- Gene Ontology Molecular Function:
- DNA binding
DNA-directed RNA polymerase activity
ribonucleoside binding - Keywords:
- DNA-directed RNA polymerase
Nucleotidyltransferase
Transcription
Transferase
Publication
- PubMed ID:
- 14702039