Names & Taxonomy

Uniprot ID:
B3KNK4
Entry Name:
B3KNK4_HUMAN
Status:
unreviewed
Protein Names:
Phosphatidate cytidylyltransferase (EC 2.7.7.41)
Organism:
Homo sapiens (Human)

Structure

Length:
445
Sequence:
MTELRQRVAHEPVAPPEDKESESEAKVDGETASDSESRAESAPLPVSADDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMIIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFTLYLIGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSVIGWKTVRMYPSQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGPNPSKLIQQFLTLRPDQQLHIFNTLRSHLIDKGMLTSTTEDE

Function

Pathway:
Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.
Catalytic Activity:
CTP + phosphatidate = diphosphate + CDP-diacylglycerol.
Gene Ontology Go:
integral component of membrane
phosphatidate cytidylyltransferase activity
CDP-diacylglycerol biosynthetic process
Gene Ontology Biological Process:
CDP-diacylglycerol biosynthetic process
Gene Ontology Molecular Function:
phosphatidate cytidylyltransferase activity
Gene Ontology Cellular Component:
integral component of membrane
Keywords:
Membrane
Nucleotidyltransferase
Transferase
Transmembrane
Transmembrane helix

Publication

PubMed ID:
14702039