Names & Taxonomy

Uniprot ID:
A8E633
Entry Name:
A8E633_HUMAN
Status:
unreviewed
Protein Names:
FGFR3 protein (Fragment)
Gene Names:
FGFR3
Gene Names Primary:
FGFR3
Organism:
Homo sapiens (Human)

Structure

Length:
480
Sequence:
TRALPEDAGEYTCPAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT

Function

Catalytic Activity:
ATP + a -L-tyrosine = ADP + a -L-tyrosine phosphate.
Gene Ontology Go:
integral component of membrane
ATP binding
protein tyrosine kinase activity
Gene Ontology Molecular Function:
ATP binding
protein tyrosine kinase activity
Gene Ontology Cellular Component:
integral component of membrane
Keywords:
ATP-binding
Membrane
Nucleotide-binding
Receptor
Transmembrane
Transmembrane helix

Publication

PubMed ID:
15489334