Names & Taxonomy

Uniprot ID:
Q9Y5R8
Entry Name:
TPPC1_HUMAN
Status:
reviewed
Protein Names:
Trafficking protein particle complex subunit 1 (BET5 homolog) (Multiple myeloma protein 2) (MUM-2)
Gene Names:
TRAPPC1 BET5 MUM2
Gene Names Primary:
TRAPPC1
Organism:
Homo sapiens (Human)

Structure

Length:
145
Sequence:
MTVHNLYLFDRNGVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDGFLAFQTSRYKLHYYETPTGIKVVMNTDLGVGPIRDVLHHIYSALYVELVVKNPLCPLGQTVQSELFRSRLDSYVRSLPFFSARAG
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Golgi apparatus, cis-Golgi network

Function

Function:
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Gene Ontology Go:
cis-Golgi network
cytosol
endoplasmic reticulum
Golgi membrane
TRAPP complex
Rab guanyl-nucleotide exchange factor activity
cellular protein metabolic process
COPII vesicle coating
ER to Golgi vesicle-mediated transport
membrane organization
positive regulation of GTPase activity
post-translational protein modification
protein N-linked glycosylation via asparagine
Gene Ontology Biological Process:
cellular protein metabolic process
COPII vesicle coating
ER to Golgi vesicle-mediated transport
membrane organization
positive regulation of GTPase activity
post-translational protein modification
protein N-linked glycosylation via asparagine
Gene Ontology Molecular Function:
Rab guanyl-nucleotide exchange factor activity
Gene Ontology Cellular Component:
cis-Golgi network
cytosol
endoplasmic reticulum
Golgi membrane
TRAPP complex
Keywords:
Complete proteome
ER-Golgi transport
Endoplasmic reticulum
Golgi apparatus
Polymorphism
Reference proteome
Transport

Publication

PubMed ID:
10582700 15489334 11805826 21269460