Names & Taxonomy
- Uniprot ID:
- Q9Y2Q3
- Entry Name:
- GSTK1_HUMAN
- Status:
- reviewed
- Protein Names:
- Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (hGSTK1) (Glutathione S-transferase subunit 13)
- Gene Names:
- GSTK1 HDCMD47P
- Gene Names Orf:
- HDCMD47P
- Gene Names Primary:
- GSTK1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 226
- Sequence:
- MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLPRKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRELWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Peroxisome
Function
- Function:
- Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).
- Catalytic Activity:
- RX + glutathione = HX + R-S-glutathione.
- Cross Reference Drug Bank:
- DB00143
- Gene Ontology Go:
- extracellular exosome
intracellular
intracellular membrane-bounded organelle
membrane
mitochondrial inner membrane
mitochondrial matrix
peroxisome
glutathione peroxidase activity
glutathione transferase activity
protein disulfide oxidoreductase activity
receptor binding
cellular oxidant detoxification
epithelial cell differentiation
glutathione derivative biosynthetic process
glutathione metabolic process
small molecule metabolic process
xenobiotic metabolic process - Gene Ontology Biological Process:
- cellular oxidant detoxification
epithelial cell differentiation
glutathione derivative biosynthetic process
glutathione metabolic process
small molecule metabolic process
xenobiotic metabolic process - Gene Ontology Molecular Function:
- glutathione peroxidase activity
glutathione transferase activity
protein disulfide oxidoreductase activity
receptor binding - Gene Ontology Cellular Component:
- extracellular exosome
intracellular
intracellular membrane-bounded organelle
membrane
mitochondrial inner membrane
mitochondrial matrix
peroxisome - Keywords:
- 3D-structure
Acetylation
Alternative splicing
Complete proteome
Peroxisome
Reference proteome
Transferase - Interacts With:
- O95273; Q8IZU0