Names & Taxonomy

Uniprot ID:
Q9Y296
Entry Name:
TPPC4_HUMAN
Status:
reviewed
Protein Names:
Trafficking protein particle complex subunit 4 (Hematopoietic stem/progenitor cell protein 172) (Synbindin) (TRS23 homolog)
Gene Names:
TRAPPC4 SBDN CGI-104 HSPC172 PTD009
Gene Names Orf:
CGI-104 HSPC172 PTD009
Gene Names Primary:
TRAPPC4
Organism:
Homo sapiens (Human)

Structure

Length:
219
Sequence:
MAIFSVYVVNKAGGLIYQLDSYAPRAEAEKTFSYPLDLLLKLHDERVLVAFGQRDGIRVGHAVLAINGMDVNGRYTADGKEVLEYLGNPANYPVSIRFGRPRLTSNEKLMLASMFHSLFAIGSQLSPEQGSSGIEMLETDTFKLHCYQTLTGIKFVVLADPRQAGIDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFGPGS
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Golgi apparatus, cis-Golgi network

Function

Function:
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Gene Ontology Go:
cis-Golgi network
cytosol
dendrite
endoplasmic reticulum
Golgi membrane
Golgi stack
synapse
synaptic vesicle
TRAPP complex
Rab guanyl-nucleotide exchange factor activity
cellular protein metabolic process
COPII vesicle coating
dendrite development
ER to Golgi vesicle-mediated transport
extracellular matrix organization
membrane organization
positive regulation of GTPase activity
post-translational protein modification
protein N-linked glycosylation via asparagine
Gene Ontology Biological Process:
cellular protein metabolic process
COPII vesicle coating
dendrite development
ER to Golgi vesicle-mediated transport
extracellular matrix organization
membrane organization
positive regulation of GTPase activity
post-translational protein modification
protein N-linked glycosylation via asparagine
Gene Ontology Molecular Function:
Rab guanyl-nucleotide exchange factor activity
Gene Ontology Cellular Component:
cis-Golgi network
cytosol
dendrite
endoplasmic reticulum
Golgi membrane
Golgi stack
synapse
synaptic vesicle
TRAPP complex
Keywords:
3D-structure
Alternative splicing
Complete proteome
ER-Golgi transport
Endoplasmic reticulum
Golgi apparatus
Polymorphism
Reference proteome
Transport
Interacts With:
Q9CQA1

Publication

PubMed ID:
11042152 10810093 14702039 16554811 15489334 11805826 19416478 21269460 21525244