Names & Taxonomy
- Uniprot ID:
- Q9UN76
- Entry Name:
- S6A14_HUMAN
- Status:
- reviewed
- Protein Names:
- Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14)
- Gene Names:
- SLC6A14
- Gene Names Primary:
- SLC6A14
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 642
- Sequence:
- MDKLKCPSFFKCREKEKVSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLEQHRGERYKDMVDPKKEADHEIPTVSGSRKPE
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Multi-pass membrane protein.
Function
- Function:
- Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner.
- Cross Reference Drug Bank:
- DB00172 DB00577 DB01610
- Gene Ontology Go:
- brush border membrane
extracellular exosome
integral component of membrane
integral component of plasma membrane
plasma membrane
vesicle
amino acid transmembrane transporter activity
neurotransmitter:sodium symporter activity
amino acid transmembrane transport
amino acid transport
cellular amino acid metabolic process
ion transport
response to toxic substance
transmembrane transport
transport - Gene Ontology Biological Process:
- amino acid transmembrane transport
amino acid transport
cellular amino acid metabolic process
ion transport
response to toxic substance
transmembrane transport
transport - Gene Ontology Molecular Function:
- amino acid transmembrane transporter activity
neurotransmitter:sodium symporter activity - Gene Ontology Cellular Component:
- brush border membrane
extracellular exosome
integral component of membrane
integral component of plasma membrane
plasma membrane
vesicle - Keywords:
- Amino-acid transport
Complete proteome
Glycoprotein
Membrane
Obesity
Reference proteome
Symport
Transmembrane
Transmembrane helix
Transport