Names & Taxonomy

Uniprot ID:
Q9UJT1
Entry Name:
TBD_HUMAN
Status:
reviewed
Protein Names:
Tubulin delta chain (Delta-tubulin)
Gene Names:
TUBD1 TUBD
Gene Names Primary:
TUBD1
Organism:
Homo sapiens (Human)

Structure

Length:
453
Sequence:
MSIVTVQLGQCGNQIGFEVFDALLSDSHSSQGLCSMRENEAYQASCKERFFSEEENGVPIARAVLVDMEPKVINQMLSKAAQSGQWKYGQHACFCQKQGSGNNWAYGYSVHGPRHEESIMNIIRKEVEKCDSFSGFFIIMSMAGGTGSGLGAFVTQNLEDQYSNSLKMNQIIWPYGTGEVIVQNYNSILTLSHLYRSSDALLLHENDAIHKICAKLMNIKQISFSDINQVLAHQLGSVFQPTYSAESSFHYRRNPLGDLMEHLVPHPEFKMLSVRNIPHMSENSLAYTTFTWAGLLKHLRQMLISNAKMEEGIDRHVWPPLSGLPPLSKMSLNKDLHFNTSIANLVILRGKDVQSADVEGFKDPALYTSWLKPVNAFNVWKTQRAFSKYEKSAVLVSNSQFLVKPLDMIVGKAWNMFASKAYIHQYTKFGIEEEDFLDSFTSLEQVVASYCNL
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm. Nucleus. Note=Associated with centrioles. Both cytoplasmic and nuclear.

Function

Function:
In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head.
Cross Reference Drug Bank:
DB00570
Gene Ontology Go:
centriole
cytoplasm
microtubule
nucleoplasm
GTP binding
GTPase activity
structural constituent of cytoskeleton
cell differentiation
microtubule-based process
multicellular organism development
spermatogenesis
Gene Ontology Biological Process:
cell differentiation
microtubule-based process
multicellular organism development
spermatogenesis
Gene Ontology Molecular Function:
GTPase activity
GTP binding
structural constituent of cytoskeleton
Gene Ontology Cellular Component:
centriole
cytoplasm
microtubule
nucleoplasm
Keywords:
Alternative splicing
Complete proteome
Cytoplasm
Cytoskeleton
Developmental protein
Differentiation
GTP-binding
Microtubule
Nucleotide-binding
Nucleus
Polymorphism
Reference proteome
Spermatogenesis

Publication

PubMed ID:
10620804 15081367 14702039 16625196 15489334