Names & Taxonomy

Uniprot ID:
Q9UBD6
Entry Name:
RHCG_HUMAN
Status:
reviewed
Protein Names:
Ammonium transporter Rh type C (Rh glycoprotein kidney) (Rhesus blood group family type C glycoprotein) (Rh family type C glycoprotein) (Rh type C glycoprotein) (Tumor-related protein DRC2)
Gene Names:
RHCG C15orf6 CDRC2 PDRC2 RHGK
Gene Names Primary:
RHCG
Organism:
Homo sapiens (Human)

Structure

Length:
479
Sequence:
MAWNTNLRWRLPLTCLLLQVIMVILFGVFVRYDFEADAHWWSERTHKNLSDMENEFYYRYPSFQDVHVMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFLQDRYIVVGVENLINADFCVASVCVAFGAVLGKVSPIQLLIMTFFQVTLFAVNEFILLNLLKVKDAGGSMTIHTFGAYFGLTVTRILYRRNLEQSKERQNSVYQSDLFAMIGTLFLWMYWPSFNSAISYHGDSQHRAAINTYCSLAACVLTSVAISSALHKKGKLDMVHIQNATLAGGVAVGTAAEMMLMPYGALIIGFVCGIISTLGFVYLTPFLESRLHIQDTCGINNLHGIPGIIGGIVGAVTAASASLEVYGKEGLVHSFDFQGFNGDWTARTQGKFQIYGLLVTLAMALMGGIIVGLILRLPFWGQPSDENCFEDAVYWEMPEGNSTVYIPEDPTFKPSGPSVPSVPMVSPLPMASSVPLVP
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Apical cell membrane

Function

Function:
Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.
Gene Ontology Go:
apical plasma membrane
basolateral plasma membrane
cytoplasmic vesicle
extracellular exosome
integral component of plasma membrane
plasma membrane
ammonium transmembrane transporter activity
ankyrin binding
amine transport
ammonium transport
cellular ion homeostasis
cellular response to nitrogen starvation
epithelial cell differentiation
homeostatic process
nitrogen utilization
organic cation transport
regulation of pH
transepithelial ammonium transport
transmembrane transport
Gene Ontology Biological Process:
amine transport
ammonium transport
cellular ion homeostasis
cellular response to nitrogen starvation
epithelial cell differentiation
homeostatic process
nitrogen utilization
organic cation transport
regulation of pH
transepithelial ammonium transport
transmembrane transport
Gene Ontology Molecular Function:
ammonium transmembrane transporter activity
ankyrin binding
Gene Ontology Cellular Component:
apical plasma membrane
basolateral plasma membrane
cytoplasmic vesicle
extracellular exosome
integral component of plasma membrane
plasma membrane
Keywords:
3D-structure
Ammonia transport
Cell membrane
Complete proteome
Glycoprotein
Membrane
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
10852913 12204676 14702039 16572171 15489334 11062476 14761968 15929723 16477434 16580862 20457942