Names & Taxonomy
- Uniprot ID:
- Q9NTN3
- Entry Name:
- S35D1_HUMAN
- Status:
- reviewed
- Protein Names:
- UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter (UDP-GlcA/UDP-GalNAc transporter) (Solute carrier family 35 member D1) (UDP-galactose transporter-related protein 7) (UGTrel7)
- Gene Names:
- SLC35D1 KIAA0260 UGTREL7
- Gene Names Primary:
- SLC35D1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 355
- Sequence:
- MAEVHRRQHARVKGEAPAKSSTLRDEEELGMASAETLTVFLKLLAAGFYGVSSFLIVVVNKSVLTNYRFPSSLCVGLGQMVATVAVLWVGKALRVVKFPDLDRNVPRKTFPLPLLYFGNQITGLFSTKKLNLPMFTVLRRFSILFTMFAEGVLLKKTFSWGIKMTVFAMIIGAFVAASSDLAFDLEGYAFILINDVLTAANGAYVKQKLDSKELGKYGLLYYNALFMILPTLAIAYFTGDAQKAVEFEGWADTLFLLQFTLSCVMGFILMYATVLCTQYNSALTTTIVGCIKNILITYIGMVFGGDYIFTWTNFIGLNISIAGSLVYSYITFTEEQLSKQSEANNKLDIKGKGAV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Endoplasmic reticulum membrane; Multi-pass membrane protein.
Function
- Function:
- Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis.
- Gene Ontology Go:
- endoplasmic reticulum membrane
integral component of membrane
pyrimidine nucleotide-sugar transmembrane transporter activity
UDP-glucuronic acid transmembrane transporter activity
carbohydrate transport
cellular glucuronidation
chondroitin sulfate biosynthetic process
embryonic skeletal system development
small molecule metabolic process
transmembrane transport
UDP-glucuronate biosynthetic process
UDP-glucuronic acid transport
xenobiotic metabolic process - Gene Ontology Biological Process:
- carbohydrate transport
cellular glucuronidation
chondroitin sulfate biosynthetic process
embryonic skeletal system development
small molecule metabolic process
transmembrane transport
UDP-glucuronate biosynthetic process
UDP-glucuronic acid transport
xenobiotic metabolic process - Gene Ontology Molecular Function:
- pyrimidine nucleotide-sugar transmembrane transporter activity
UDP-glucuronic acid transmembrane transporter activity - Gene Ontology Cellular Component:
- endoplasmic reticulum membrane
integral component of membrane - Keywords:
- Alternative splicing
Complete proteome
Endoplasmic reticulum
Membrane
Polymorphism
Reference proteome
Sugar transport
Transmembrane
Transmembrane helix
Transport