Names & Taxonomy
- Uniprot ID:
- Q9NSA0
- Entry Name:
- S22AB_HUMAN
- Status:
- reviewed
- Protein Names:
- Solute carrier family 22 member 11 (Organic anion transporter 4)
- Gene Names:
- SLC22A11 OAT4
- Gene Names Primary:
- SLC22A11
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 550
- Sequence:
- MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQEAVTVESTSL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.
- Cross Reference Drug Bank:
- DB00345 DB00168 DB01053 DB00887 DB00456 DB01326 DB01327 DB01329 DB00493 DB01212 DB00501 DB00286 DB00586 DB01160 DB00917 DB00254 DB00783 DB00695 DB01050 DB00328 DB01009 DB00563 DB01017 DB01051 DB00595 DB00812 DB00554 DB00175 DB01032 DB00936 DB00759 DB00495
- Gene Ontology Go:
- apical plasma membrane
external side of plasma membrane
extracellular exosome
integral component of plasma membrane
plasma membrane
inorganic anion exchanger activity
organic anion transmembrane transporter activity
sodium-independent organic anion transmembrane transporter activity
anion transmembrane transport
organic anion transport
sodium-independent organic anion transport
transmembrane transport
urate metabolic process - Gene Ontology Biological Process:
- anion transmembrane transport
organic anion transport
sodium-independent organic anion transport
transmembrane transport
urate metabolic process - Gene Ontology Molecular Function:
- inorganic anion exchanger activity
organic anion transmembrane transporter activity
sodium-independent organic anion transmembrane transporter activity - Gene Ontology Cellular Component:
- apical plasma membrane
external side of plasma membrane
extracellular exosome
integral component of plasma membrane
plasma membrane - Keywords:
- Alternative splicing
Cell membrane
Complete proteome
Glycoprotein
Ion transport
Membrane
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport