Names & Taxonomy
- Uniprot ID:
- Q9NS82
- Entry Name:
- AAA1_HUMAN
- Status:
- reviewed
- Protein Names:
- Asc-type amino acid transporter 1 (Asc-1) (Solute carrier family 7 member 10)
- Gene Names:
- SLC7A10 ASC1
- Gene Names Primary:
- SLC7A10
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 523
- Sequence:
- MAGHTQQPSGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPEEEENGPCPPSLLPATDKPSKPQ
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Function:
- Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse.
- Gene Ontology Go:
- dendrite
integral component of plasma membrane
membrane
plasma membrane
antiporter activity
D-serine transmembrane transporter activity
L-serine transmembrane transporter activity
neutral amino acid transmembrane transporter activity
amino acid transport
blood coagulation
D-alanine transport
D-serine transport
ion transport
L-serine transport
leukocyte migration
neutral amino acid transport
transmembrane transport - Gene Ontology Biological Process:
- amino acid transport
blood coagulation
D-alanine transport
D-serine transport
ion transport
leukocyte migration
L-serine transport
neutral amino acid transport
transmembrane transport - Gene Ontology Molecular Function:
- antiporter activity
D-serine transmembrane transporter activity
L-serine transmembrane transporter activity
neutral amino acid transmembrane transporter activity - Gene Ontology Cellular Component:
- dendrite
integral component of plasma membrane
membrane
plasma membrane - Keywords:
- Amino-acid transport
Complete proteome
Disulfide bond
Membrane
Phosphoprotein
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport