Names & Taxonomy

Uniprot ID:
Q9NRK6
Entry Name:
ABCBA_HUMAN
Status:
reviewed
Protein Names:
ATP-binding cassette sub-family B member 10, mitochondrial (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2)
Gene Names:
ABCB10
Gene Names Primary:
ABCB10
Organism:
Homo sapiens (Human)

Structure

Length:
738
Sequence:
MRGPPAWPLRLLEPPSPAEPGRLLPVACVWAAASRVPGSLSPFTGLRPARLWGAGPALLWGVGAARRWRSGCRGGGPGASRGVLGLARLLGLWARGPGSCRCGAFAGPGAPRLPRARFPGGPAAAAWAGDEAWRRGPAAPPGDKGRLRPAAAGLPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAVLDQGKITEYGKHEELLSKPNGIYRKLMNKQSFISA
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.

Function

Function:
May mediate critical mitochondrial transport functions related to heme biosynthesis.
Gene Ontology Go:
integral component of mitochondrial membrane
mitochondrial inner membrane
ATP binding
ATPase activity, coupled to transmembrane movement of substances
transporter activity
transmembrane transport
transport
Gene Ontology Biological Process:
transmembrane transport
transport
Gene Ontology Molecular Function:
ATPase activity, coupled to transmembrane movement of substances
ATP binding
transporter activity
Gene Ontology Cellular Component:
integral component of mitochondrial membrane
mitochondrial inner membrane
Keywords:
3D-structure
ATP-binding
Acetylation
Complete proteome
Membrane
Mitochondrion
Mitochondrion inner membrane
Nucleotide-binding
Polymorphism
Reference proteome
Transit peptide
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
10922475 16710414 15489334 7766993 19608861 21269460 24275569 25944712 23716676 11829140 16959974