Names & Taxonomy
- Uniprot ID:
- Q9HB63
- Entry Name:
- NET4_HUMAN
- Status:
- reviewed
- Protein Names:
- Netrin-4 (Beta-netrin) (Hepar-derived netrin-like protein)
- Gene Names:
- NTN4
- Gene Names Primary:
- NTN4
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 628
- Sequence:
- MGSCARLLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGRKLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAICTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGTHVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCPILNPGLEYLVAGHEDIRTGKLIVNMKSFVQHWKPSLGRKVMDILKRECK
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted, extracellular space, extracellular matrix, basement membrane
Function
- Function:
- May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.
- Gene Ontology Go:
- basement membrane
plasma membrane
axon guidance
extracellular matrix organization
neuron remodeling
regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling - Gene Ontology Biological Process:
- axon guidance
extracellular matrix organization
neuron remodeling
regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling - Gene Ontology Cellular Component:
- basement membrane
plasma membrane - Keywords:
- Alternative splicing
Basement membrane
Complete proteome
Disulfide bond
Extracellular matrix
Glycoprotein
Laminin EGF-like domain
Polymorphism
Reference proteome
Repeat
Secreted
Signal - Interacts With:
- P26371