Names & Taxonomy
- Uniprot ID:
- A4D1Q0
- Entry Name:
- A4D1Q0_HUMAN
- Status:
- unreviewed
- Protein Names:
- Muscarinic acetylcholine receptor
- Gene Names:
- CHRM2 hCG_1641225 tcag7.414
- Gene Names Orf:
- hCG_1641225 tcag7.414
- Gene Names Primary:
- CHRM2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 466
- Sequence:
- MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
- Gene Ontology Go:
- asymmetric synapse
axon terminus
cell junction
dendrite
integral component of plasma membrane
neuronal cell body
postsynaptic membrane
symmetric synapse
drug binding
G-protein coupled acetylcholine receptor activity
regulation of heart contraction
regulation of smooth muscle contraction - Gene Ontology Biological Process:
- regulation of heart contraction
regulation of smooth muscle contraction - Gene Ontology Molecular Function:
- drug binding
G-protein coupled acetylcholine receptor activity - Gene Ontology Cellular Component:
- asymmetric synapse
axon terminus
cell junction
dendrite
integral component of plasma membrane
neuronal cell body
postsynaptic membrane
symmetric synapse - Keywords:
- Cell junction
Cell membrane
G-protein coupled receptor
Membrane
Postsynaptic cell membrane
Receptor
Synapse
Transducer
Transmembrane
Transmembrane helix